Friday, March 30, 2007

What is my acne really trying to tell me?

by Sarah Rhodes

When using acne solutions, make sure that you follow the directions. Overuse of the product can cause as many problems as under use of the product. Follow the directions to the letter, unless your doctor or dermatologist advises otherwise. The best acne solutions will contain both topical treatment, as well as oral treatment. Acne starts on the inside of the body, but it is prevented and healed on both the inside and outside of the body.

There are two dermatologist tested ways to facilitate the healing of acne, one is the use of Tretinoin, it's a form of vitamin A, which speeds up the skin's healing and renovation process shortening the inflammation period, thus preventing acne scars. The other treatment used by most dermatologists for acne scar prevention is the use of Aplpha-Hydroxy Acids of AHA's and Beta-Hydroxy Acids or BHA's. These help the skins remodeling process, with the right concentration and proper application; these can also prevent acne scars.

It makes sense to cleanse and nourish from both the INSIDE and OUT. Your face and body do not need more clogging, synthetic oils and lotions. They need real nutrition that can make a difference when applied topically as well as nutrition internally to enhance detoxification and a healthy blood supply to the vessels beneath the skin's surface.

Topical retinoid acid, a modified form of vitamin A has been a great improvement. Improved versions of this medicine greatly reduce the irritation it can cause. Other acne treatments are sometimes used in combination. Such acne treatments include Azelaic acid cream, Benzoyl peroxide, Alpha-hydroxy acids (such as lactic acid, glycolic acid and gluconic acid), antibiotic pills (of used unwisely, they can lead to antibiotic resistance), topical antibiotics (gels, lotions and solutions), contraceptive pills for women, and Sotret or Accutane for severe acne. Accutane and Sotret have several side effects, including birth defects. Women with severe acne problems that choose these treatments should use alternative birth control.

Stress is commonly blamed for the development of acne. Stress can have many physiologic effects on the body, including changes in hormones that may theoretically lead to acne. In some cases the stress may actually be caused by the acne lesions, not the other way around! If the acne is being treated effectively, stress is not likely to have much impact on the majority of people.

In many of your natural skincare product you will find properties included such as Cinnamon, Neem, Tea Tree oil, and Echinacea. These items are known to have natural forms of antibacterial and antimicrobial properties. Unlike many of the herbs and spices, many of them may not have proven effects other than the Tea Tree plant. It has been proven to be effective against bacteria that cause blemishes, and usually the concentration level should be around 5 - 10% to show results. However, most skin care products only offer less than 1%, which is considered ineffective.
Article Source: http://www.goarticles.com
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Wednesday, March 28, 2007

Adult Acne? - Don't Feel You're Alone. It Happens!

by Robert G. Knechtel

While we think of acne as a teenage affliction, adults in surprising numbers are vulnerable to this skin disorder. Both teenagers and adults with acne often react by wanting to isolate. However, as a grown-up you should take some comfort in the knowledge that you are by no means alone.

Statistics reveal that, at some time in their lives, 25% of adult men and 50% of adult women will experience an acne outbreak more serious that an occasional zit or two. So, the teenage stereotype basically is a myth.

Adult Acne Solutions - Medicine and Other Approaches

Almost always, the first thing that comes to mind for treating adult acne in its more virulent manifestations is what choices among the many acne medicines would make sense. Those under care of a dermatologist likely will be prescribed one or more of the most commonly indicated acne medications, including Accutane, Retin-A, Erythromycin, Tetracycline and Doxycycline.

For really severe adult acne, i.e. the kind that can scar, many physicians are quick to prescribe Accutane. This is a very powerful medication that attacks the underlying cause of acne from the inside out by shrinking oil glands. An excess of skin oil is the underlying cause of acne. A natural oil called sebum builds to abnormal levels, clogging skin pores, leading to the growth of microbes which are responsible for acne flare-ups.

One of Accutane's huge drawbacks is its well documented incidence of side effects. First, it can produce severe birth defects in pregnant women. Secondly, many experience mild to moderate aches in the joints and muscles as well as dry and cracked lips, dry skin, dry mouth and dry nose.

There are many who claim, on the other hand, that their adult acne is especially susceptible to treatment with benzoyl peroxide, an ingredient found in several of the over-the-counter creams and ointments. Excellent results are often obtained when these remedies are combined with good diet and proper hydration.

Under any circumstances, if you do nothing else, drink plenty of water! Your skin needs water for hydration i.e. moisturizing. As an adult acne victim, your skin will suffer from dehydration. Control of acne is also enhanced by eating a balanced diet with plenty of fruits and vegetables.

Combining diet and hydration with vitamins is also recommended. Vitamins A, B, C, and E are believed to have beneficial effects, especially vitamin A. The latter helps to control hormonal levels which in turn controls production of sebum. In addition, vitamin A operates as an antioxidant which strengthens skin tissue.

Beyond medication, diet and hydration there are more invasive treatment techniques to which many turn to cope with the consequences of adult acne.

Microdermabrasion

In cases of mild acne scarring, microdermabrasion is becoming more of a treatment of choice. However, it is not useful for severe scarring. Moreover, those of advanced age or with sensitive skin usually are not candidates for this technique. One of its advantages is that the treatment is brief and results become apparent very quickly.

Laser Skin Resurfacing

Laser skin resurfacing is a relatively new process to come on the scene in adult acne treatment. By using a laser light, this method can reach even deeper skin layers than microdermabrasion.

Chemical Peeling

Improvement in skin discoloration and age spots, as well as light freckling and scarring also can be brought about by chemical peeling. It will stimulate growth of new, healthy skin cells which is quite beneficial for adult acne sufferers.

What is the Price of All This Adult Acne Treatment?

Costs for acne remedies can vary from just a few dollars for a tube of over-the-counter medication to thousands of dollars for more proactive approaches. Antibiotics and prescribed topical creams and lotions can cost upwards of $200 per month. Skin resurfacing treatments such as microdermabrasion, chemical peeling, lasers, etc. can cost from less than $100 to thousands, depending on where treatment is rendered. If you suffer from adult acne, watch out in Beverly Hills!
Article Source: http://www.goarticles.com
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Monday, March 26, 2007

Are You Using Anti-Freeze To Treat Your Acne?

By Pam Mitchell

If your reading this I will assume that your life has some how been impacted my the highly irritating disease called acne. It is not surprising that you have been affected by it in some way seeing as though it is the most common of the skin diseases and affects close to 17 million people in the United States. It is most common among young adults ranging from 12-14, nearly 85 percent have acne; however acne still occurs among people who are below and above this age group. Acne will seize to exist for some by age 30, however for many it lasts until they are in their fifties.

Many people use products on their faces and other areas of their body that prevent acne. What many people neglect to investigate is exactly what they are putting on their skin. The answer is harmful chemicals. Your acne products may contain chemicals that, in high doses, are banned because they are so lethal. Some of these chemicals include Propylene Glycol which is a cosmetic form of mineral oil that is found in automatic brake fluid, hydraulic fluid and industrial antifreeze. According to the Material Safety Data Sheet users are warned to avoid skin contact as it is a strong skin irritant and can cause liver abnormalities and kidney damage. Alcohol is commonly used in acne products as well. Take note that it is not the same as the alcohol that is found in alcoholic drinks, it is much more dangerous. Alcohol can make your bodies tissue more vulnerable to carcinogens, an agent directly involved in the promotion of caner. Glycerine, which is a syrupy liquid chemically produced by combining water and fats, is also very commonly used in acne products. Most products with glycerine in their ingredients claim to be "replenishing" or "moisturizing" when in fact using glycerine on your skin only makes your skin progressively worse by drying your skin from the inside out. Other products this chemical is found in are insect repellent, car glaze and paint cleaner.

After reading these facts I hope you are as disgusted and, above all, worried as I am. You may be cleaning your skin with the same chemicals you use in your cars engine. you may be putting a chemical on your skin that you can also use to polish your floors.

The best method for curing acne is naturally whether it is a home remedy or a natural face washing product. Also, to prevent the cause of acne it is best to use natural cosmetics and lotions/moisturizers on your skin.

Article Source: http://EzineArticles.com/?expert=Pam_Mitchell

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Friday, March 23, 2007

Oral Retinoid Acne Treatment

By: Asanka Samaranayake

Isotretinoin can be obtained in the topical form (i.e. in the form of creams, gels and lotions) as well as in the oral capsule form.

Oral isotretinoin, also known as Roaccutane (Roche), reduces the secretion of oil (sebum), from the sebaceous glands found in the skin. As a result of this, less oil secretion means that there is less of it for bacteria to thrive on. This therefore leads to decreased inflammatory/infection rates of the hair follicle leading to the prevention of acne formation.
It is primarily used for nodulo-cystic acne ('hard raised pus-filled spots'), conglobate acne (this rare type of acne develops on the back, bottom and thorax. It is an accumulation of pustules and cysts, and this may be due to a strong bacterial infection) and severe acne/scarring.

It is usually given to people who have not responded to:
1.Acne creams (benzoyl peroxide, retinoids etc.)
2.Antibiotics (erythromycin, tetracyclines etc.)
Oral isotretinoin has also been shown to be quite useful in women who are in the 3dr and 4th decades of life. Studies have shown that acne developing in women (in the 3rd and 4th decades of life) is not usually responsive to antibacterial treatment; Roaccutane has shown efficacy in these cases.

Isotretinoin is quite a toxic drug and a lot of care and supervision must be undertaken when taking this medication. It should always be prescribed by a consultant dermatologist.

The course of treatment is usually 16 weeks. In many cases, repeat treatments are not required although can be undertaken with the clinical consent of your consultant dermatologist.

Main Side effects of isotretinoin include
1.Sever dryness of the skin and mucous membranes (such as the mouth, nose etc.)
2.Nose bleeds
3.Joint pains
4.There are many more side effects which have been associated with this drug; these are rare and can be obtained from any drug formulary or from the Roaccutane website.

Contraindications
1.This drug is highly teratogenic ( meaning it can be very harmful to the developing baby during the course of pregnancy) and MUST not be given to women of child bearing age unless they practise effective methods of contraception
2.People with liver disease should not take this medication as it can further impair the liver and exacerbate the disease process
3.Patients with kidney disease are advised not to take this and guidance from a consultant dermatologist should be taken
4.Patients with high cholesterol are strongly advised not take this medication and regular liver function tests should be performed in all patients before treatment with oral isotretinoin is commenced

Efficacy
Isotretionoin is very good at obliterating acne but at the cost of some side effects which may cause problems in some patients. Although these side effects are rare, they can still occur and, if experienced, you must consult your doctor for advice. Many patients have reported good results with oral isotretinoin and usually only one course of treatment is required. If you are considering this form of treatment, it would be in the your best interest to seek medical advice from a dermatologist.

Article Source: http://www.articlebankonline.com

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Tuesday, March 20, 2007

How does Accutane Work?

How does Accutane work so well against acne in so many cases?

Because it accomplishes several things simultaneously that no other medicine can do all at the same time:

  • reducing oil production (sebum) by reducing sebaceous glands,
  • decreasing cell build up leading to whiteheads or blackheads,
  • killing acne bacteria deep inside the skin, and
  • reducing inflammation.

Normal oil production in your skin will return when you complete your Accutane course. The sebaceous glands will slowly grow larger in size, but will never reach their original size.

Accutane is generally prescribed for stubborn moderate to severe or nodular acne that is resistant to several different treatments. It can quickly reduce severe acne inflammatory lesions by 90%. ( Source: Journal of the American Academy of Dermatology, November 2001, Supplemental, pages 188–194).

But dermatologists remain careful with who they give a prescription to. Accutane is not a true “cure” and to date there is no cure available for acne, only treatments.

For the remaining users where accutane does not work the first time around, they may be recommended to wait for about 6 months before they try a second course of Accutane. If their acne returns after the second course, the drug has likely failed. For 10% of users, acne comes back after one year. For 25% of users, acne comes back after two years.

If your acne returns, you may want to try antibiotics or you could still try Accutane again.

How does accutane work over a long period of time?

Isotretinoin doesn’t always work. Sometimes it makes acne worse before it gets better. Sometimes, it makes acne much worse than it originally was and causes horrible scarring.

How is accutane prescribed?

Generally accutane is introduced at a very low dose and is steadily increased over many weeks. There actually are no specific guidelines as to how much should be prescribed to each person. However, research shows that a total dose of around 120mg per kilogram of an individual’s body weight is enough to banish acne for some time.

There are two schools of thought when it comes to tackling acne with accutane:

  1. The high-dose: This is the method most used in the US where it is usually used for women. This means they would have to endure any potential side effects during the first few months.
  2. The low-dose: This refers to consuming a lower than average dose each day, or less over a longer duration. This results in less side effects during the initial months with the exception of pregnancy.
(Source: Preston, Lydia. Breaking Out. New York: Fireside, 2004.)

Usually all other prescription acne medication is discontinued while on Accutane.

Take the medicine with food, you can take the entire daily dose with supper, this increases the absorption of the medicine.

How do I know if Accutane will work for me?

There is no way to know if Accutane will work for you or if you will suffer from any of its side effects. However, you can gather your own opinion by reading some accutane journals. You may even think about keeping your own Accutane journal if you decide to use it and get a prescription from your doctor.

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Monday, March 19, 2007

Accutane Medicine For Acne - Uses, Dosage & Side Effects

By: Alien
Accutane is a powerful drug used in the treatment of acne. Four to five months of isotretinoin treatment usually leads to clearing of acne for one year or more after the medicine is stopped. Most other acne-controlling medicines are antibacterial agents, which are effective only if the medicine is used daily.
Accutane is a form of vitamin A. So it decreases the amount of sebum (oil) that is released by the sebaceous (oil) glands, and it also increases that rate at which the skin renews itself.
Accutane Dosage
The usual dose for Accutane is 0.5 to 1 milligram per 2.2 pounds of body weight, divided into 2 doses daily, for 15 to 20 weeks.
For very severe cases, your doctor may also increase the daily dose to as much as 2 milligrams per 2.2 pounds.
Uses of Accutane
*Accutane is used to treat severe nodular acne that has not responded to other treatments such as antibiotics.
*Isotretinoin is used to treat certain other skin conditions and some types of cancer.

Side Effects of Accutane
Stop using Accutane and call your doctor at once if you have any of these serious side effects:
* Blurred vision, sudden and severe headache or pain behind your eyes, sometimes with vomiting
* Hearing problems, hearing loss, or ringing in your ears
* Seizure.
* Depressed mood, trouble concentrating, sleep problems, crying spells, aggression or agitation, changes in behavior, hallucinations, thoughts of suicide or hurting yourself
* Sudden numbness or weakness, especially on one side of the body

Continue taking Accutane and talk to your doctor if you have any of these less serious side effects:

* Discomfort with contact lenses;
* Joint pain, back pain;
* Feeling dizzy, drowsy, or nervous;
* Dryness of the lips, mouth, nose, or skin; or
* Cracking or peeling skin, itching, rash, changes in your fingernails or toenails.

Warnings and precautions before taking Accutane

*Accutane is a powerful, "last resort'' medication for severe acne;
*You must not take Accutane if you are pregnant or may become pregnant during treatment;
*If you are allergic to isotretinoin, any other medications, parabens (a preservative), or any of the ingredients in isotretinoin capsules, then you should tell your doctor and pharmacist.
*You should also be avoided hair removal by waxing, laser skin treatments, and dermabrasion such as surgical smoothing of the skin while you are taking isotretinoin.
*This drug must not be used during pregnancy. If you become pregnant or think you may be pregnant, then you should inform your doctor immediately.
*Do not take vitamin supplements containing vitamin A during treatment with isotretinoin. This could cause increased side effects.
*Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Drug Interaction :-

If you are taking Accutane with certain other drugs, then it may be increased, decreased, or altered the effects of medicine. So it is especially important to check with your doctor before combining Accutane with the others. While taking Accutane, do not take vitamin supplements containing vitamin A. Because accutane and vitamin A are chemically related; taking them together is like taking an overdose of vitamin A. Remember, too, that Accutane should not be combined with tetracycline antibiotics such as including Doryx, Minocin, and Vibramycin.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a Accutane overdose may include:

* Stomach pain
* Warmth or tingling under the skin
* Swelling of the lips
* Loss of balance or coordination.
* Abdominal pain
* Dizziness
* Dry or cracked lips
* Facial flushing
* Incoordination and clumsiness
* Headache
* Vomiting

After taken Accutane if you feel that overdose is suspected, then you should contact with your doctor immediately. Because it may lead to another serious effect.

Article Source: http://www.articlewheel.com

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Accutane - a Magic Acne Cure or a Dangerous Drug?

By Tanya Turner
How Accutane works? Accutane is derived from vitamin A. It works by decreasing the amount of oil released by the oil glands; it also increases rejuvenating ability of your skin. Accutane can cure very severe cases of acne and for many teenagers it is the last hope. However, you should be very careful about its side effects, especially if you are a girl.
The scariest side effect is that if a girl becomes pregnant while taking Accutane or 1 month after the treatment, the risk of a birth defect is very high. Some teens are sexually active; some aren't. Some are responsible about birth control while others don't worry about it. If you have a daughter who is sexually active, you will have to explain to her that the risk is real and very serious, so she'll have to take birth control pills along with Accutane. Well, of course, for boys this is not a problem, but there are other side effects as well.
Accutane can cause dry and itchy skin, muscle and joint pain, irritated eyelids, decreased night vision, nosebleeds and headaches. It also can provoke depression and suicidal thoughts. Of cause "may cause" doesn't mean that you will suffer from all this. But you will have to watch out for some of the symptoms mentioned above.
Important thing to remember is that Accutane is derived from vitamin A. So you shouldn't take any supplements that contain vitamin A, while going through your treatment. Also stay away from the sun, because this drug makes your skin more sensitive to sunburn.
And one more thing, Accutane doesn't give a 100 percent effect. Many patients had success with Accutane. Otherwise dermatologists wouldn't prescribe it. However, while it is recorded to be very effective in curing acne, for some people it simply doesn't work. So, if you don't see significant improvement, you might have to accept the fact that this drug is not for you.
Before you decide to give Accutane a go, make sure that you explored other options. For example, while ordinary cleansers from a local supermarket aren't all that effective, Proactiv Solution gives very high rate of success. AlsoArticle Search, don't underestimate the power of alternative acne treatments - some produce very good results.

Source: Free Articles from ArticlesFactory.com
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Thursday, March 15, 2007

Should You Take Accutane to Treat Your Acne?

By Hector Morales
Among the most severe forms of acnes that need to be treated by special medication are nodular acne and cystic acne. A popular prescribed medication used for treating these forms of acnes is Accutane. This medication is usually applied after other treatments haven't had any positive effect on the acne condition. Cystic acne is characterized by nodules that form under the skin. With time, these nodules become harden and finally turn into painful cysts.

If you have tried different treatments and none of them have had the effects you've expected, you might be tempted to make use of Accutane as an ultimate treatment for your acne. However, you should be aware of the possible side effects that this drug can cause before making the decision to take this medication.

There are cases in which Accutane has been found to be effective in treating severe types of acne such as cystic acne. Again, unfortunately, this medication can have serious side effects. Therefore, before taking this drug, you will usually be asked to read and sign a form covering these side effects. You can only use Accutane until you understand and agree with the possible negative effects that this medication could cause you.

Among the worst possible side effects caused by Accutane is that it can cause serious birth defects. Experts recommend that women who are or plan on using Accutane take a pregnancy test every month. This test is simply to make sure the drug is stopped should they become pregnant. In fact, physicians don't recommend taking Accutane for women who plan to become pregnant. On the other hand, experts also suggest that it is safe for women to get pregnant only after having stopped taking the drug for at least a month. This will prevent women from going through a possible miscarry during pregnancy, premature birth, or stillbirth. So it is really important to consult a physician to learn about all the possible side effects in women caused by Accutane.

Another negative side effect that Accutane can cause in acne sufferers is the development of serious mental problems. In fact, many patients with these mental problems can even result in suicide! Some of the most common symptoms associated with these mental problems include: feeling angry, empty, sad or anxious, irritated, loss in social activities, sleeping too little or too much, changes in weight or appetite and thoughts of suicide. Accutane is a very powerful drug and these are only a few of the possible side effects this drug has been reported to cause. So, it is very recommended to consult your doctor immediately if you experience any of the above-mentioned symptoms or any other feeling associated with depression.

Some of the other different adverse physical effects linked to Accutane include the following: muscle aches, lip inflammation, itching, inflammation of the mucous membrane on the eyes, and dry mouth, nose, or skin. Also, patients taking this drug are subject to experiment more serious side effects such as abnormal liver enzymes and decreased levels of blood cholesterol, lipid, and triglyceride. Because the negative side effects Accutane can produce are so extensive, most patients are generally monitored by a physician. As soon as the physician finds out that the drug is causing any of the mentioned side effects, patients are then recommended to stop its usage. The good news is that for most patients, these side effects usually disappear not long after stopping taking Accutane.

As one of the most preferred acne treatments, Accutane can be a very effective prescribed medication used against serious forms of acne. If you've tried many treatments and you have not had any positive results, then Accutane could be your ultimate solution. However, as you might know by now, the most recommended advice is to consult a professional physician who can help you decide whether or not you should try this acne medication.

Article Source: http://EzineArticles.com/?expert=Hector_Morales

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Wednesday, March 14, 2007

Using Accutane - Roaccutane

By Amy Steel

If all other acne treatments fail, you may find yourself looking eagerly towards a course of Accutane / Roaccutane, which many people have come to view as a "wonder drug" for treating acne.

What is Accutane?

Accutane, also marketed as Roaccutane , is a Vitamin A derivative. It is used for the treatment of severe inflammatory or nodular-cystic acne.

How Does Accutane Work?

Accutane decreases the amount of oil produced by the skin's sebaceous (oil) glands. It will take a while to work (6-8 weeks), in fact, sometimes acne gets worse during the first month or so of treatment. Side effects, such as lip dryness, begin before the acne starts to clear.

The Benefits of Accutane

Accutane isn't a permanent cure for acne, although if you suffer from teenage acne, it often has the effect of buying time until nature clears your skin. You may be acne-free for months, even years, after you finish taking Accutane. Acne re-occurs in less than 12 months in about 10% of users, so there's a 90% chance you'll be free of acne for more than one year after the completion of a course.

This medication is usually started in small doses and upped until the acne responds. Then it is cycled as necessary over a 4-5 month period, the aim being to reduce the body's dependency on the drug.

The Drawbacks of Accutane

There's no denying the importance of the breakthrough Accutane represents in terms of providing an effective treatment for acne, but the decision to start taking it isn't one to be hurried into.

The reason for this is that as drugs go, it's pretty toxic - hard on the liver and the body's ability to process cholesterol. Most seriously, it's known to cause severe birth defects, including mental retardation and physical malformations in unborn babies, so if you're a woman, pregnancy is a no-no while you're on Accutane - in fact, doctors recommend that you use two forms of contraception because Accutane has been known to interfere with the effectiveness of hormone-based contraceptives.

Other, (mostly) less serious side effects include the following: *

Chapped lips 90%
Dry skin and itching 80%
Dryness of nose, mild nosebleed 80%
Irritation of the eyelids and eyes 40%
Joint and muscle pains 15%
Temporary hair thinning 10%
Rash 7%
Intestinal symptoms 5%
Urinary symptoms 5%
Headache 5%
Increased sensitivity to sunburn 5%
Decreased night vision <1%
Depression, thoughts of suicide <1%

*% figures refer to the proportion of users who report suffering these symptoms when taking Accutane.

Getting Access To Accutane

In many countries, access to Accutane is by prescription only, with that prescription having to come from a dermatological specialist. In addition, dermatologists and pharmacists in the U.S are required by the FDA's iPledge program to subject would-be users to fairly rigorous procedures to determine suitability/eligibility for the drug.

While it can be difficult, frustrating and expensive to obtain Accutane from a dermatologist, we strongly advise against buying Accutane online. As I've already pointed out, the drug is highly toxic, and because of this is started in small doses and then cycled through a 4-5 month period while your body's response to it (particularly your liver and cholesterol levels) are monitored via blood tests. It's just too tempting to ignore these safeguards if you're getting those meds in the post, with no-one giving you hassle, but believe me, if you're unlucky, this stuff can cause you bigger headaches than acne, so please, don't cut corners!

I know that despite my best efforts here, some of you will ignore what I've just said, so if you feel you must buy your Accutane off prescription, at least do it via a reputable source which will provide the information you need to take the drug with a minimum degree of safety.

If you are going to use Accutane without a prescription, you should make sure you follow the basic guidelines for taking the drug and looking after your health while you're on it. I've outlined them below.

Directions for taking Accutane

Take Accutane two times a day with a meal. Swallow the capsule, don't suck or chew it. Take it with a full glass of water, milk, or other non-alcoholic liquid.

Start with the lowest dose of Accutane (10mg). If your body is not reacting after 6-8 weeks, you may consider upping the dosage.

Ideally, you should take regular blood tests whilst you are on Accutane. These tests must be done when you have fasted for 12 hours (no breakfast), so that the blood fat determinations are reliable. A baseline blood chemistry test should be taken before you start your course. Don't be afraid to go seek out a physician to give you the test - you won't get into trouble, even though you may be nagged…!

Regardless of the state of your skin, you should ensure that you do not continue to take Accutane beyond 20 weeks, as your body cannot tolerate long periods of being subjected to such a toxic drug. If you find the acne comes back, go see your doctor - please!

After you finish taking Accutane, there should be at least a 2-month "rest period" during which you are off the drug. This is because your acne may continue to get better even though you are no longer taking Accutane. If you are still growing, you may need a longer "rest period."

Tuesday, March 13, 2007

Thinking of Taking Accutane for Your Acne?

By C. L. Jackson

Nodular acne and cystic acne are some of the most painful forms of acne possible. Nodular acne appears as solid, domed lesions that occur very deep in the skin, surrounded by redness and inflammation. Cystic acne occurs when the sebaceous glands in the skin have a sticky lining that prevents easy cellular shedding. The dead cells block the glands which swell with oil secretion and eventually break into cysts. Both these types of acne can be extremely painful, and both pose the threat of scarring if left untreated. When severe acne has been treated with mild to moderate medication without a positive response, many dermatologists recommend Accutane.

Accutane (or Isotretinoin) is a derivative of vitamin A that is taken orally by acne patients, generally over a period of 16 to 25 weeks. The immediate effect of this drug is a quick and dramatic (though short-term) reduction in sebum production by the sebaceous glands. Without sebum creating pressure on the pore or gland, the nodules and cysts stop forming and the skin can start to heal. Accutane is also thought to decrease skin bacteria and help reduce inflammation in the skin follicles. Although acne may get worse before it starts to improve, the results generally start to show by the third month, and once the initial course of Accutane is finished, studies show that approximately 90% of patients have clear skin for at least a year. Should acne reappear after that time, patients claim that it is usually much more manageable. Some acne patients do end up taking a second course of Accutane, once given an appropriate recovery period from the first course, and this is also frequently very effective, sometimes able to stop nodular or cystic acne altogether.

The positive results that acne patients experience with Accutane can be, without question, tremendous. However, taking this drug to treat acne does not come without significant risk; there are many side-effects associated with Accutane. Milder side-effects include (but don't stop at) dry and cracked lips, dry eyes and skin, and increased sun sensitivity. More serious side-effects include slowed wound healing, nosebleeds, and even in some cases, depression. (These are only a few of the side-effects. To learn about the rest and the likelihood of experiencing them, consult a doctor or a dermatologist.)

Although these side-effects might sound like only a mild annoyance when compared to painful and embarrassing acne, Accutane is very hard on the skin and on the body organs. Dermatologists often suggest that non-emergency surgeries be put off until long after a course of Accutane in order to give the skin time to bounce back from its frail and delicate state. Cosmetic surgeries especially are to be avoided, as are procedures like waxing body hair which requires the skin to be robust. The liver has a particularly difficult time with Accutane, and can be seriously impaired along with the immune system. The most serious consequence of taking Accutane happens if a woman taking this drug becomes pregnant during the course of treatment. Accutane has debilitating effects on a developing fetus, causing severe birth defects and sometimes even fetal death.

Should you decide to approach your dermatologist to begin Accutane acne treatment, there is a process you must go through before you will even get considered for a prescription. Blood tests will be performed to determine pre-treatment liver and kidney function, as well as to monitor blood count and blood fats. Women will have an additional blood test to ensure that they are not pregnant at the time they plan to start taking Accutane, and it will be emphasized many, many times that they should not, under any circumstances, get pregnant during the treatment or for at least 30 days afterward. Female Accutane patients will have to commit to two forms of contraception, starting a month before the treatment, and extending an extra month at the end. And for both male and female patients, some dermatologists recommend psychological screening and then continuous monitoring by psychiatrists or therapists to ensure that depression doesn't become a problem.

If you're considering starting a course of this drug, do the research and become informed. There are several reasons that a dermatologist may recommend against Accutane, depending on your personal and family history. Above all, don't give up on looking for an acne medication that works well for you. There are more acne treatment options on the market now than ever before, so acne is never without hope.

Article Source: http://EzineArticles.com/?expert=C._L._Jackson

Monday, March 12, 2007

What is Accutane And is it Right For Me?

By: Heather Colman

Accutane is a prescribed medication used for treating serious forms of acne that haven't responded well to other treatments such as nodular acne and cystic acne.

What is Acne?
Acne is formed when excess oils clog skin pores and cause a build-up to occur. If left alone, they, in turn, manifest themselves into pimples. This is only the beginning.

Sometimes, these pimples can turn into nodules, which are often painful and remain on the skin for a longer period of time. Over that time, the nodules can turn into cysts, which often require draining by a physician.

This type of acne can persist for weeks, or sometimes, even months, and is one of the most severe types. If the treatment you have sought isn't responding, you might consider Accutane as a possible treatment. There are, however, some things you should know before making the decision to take this medication.

Acne Treatment
There are literally hundreds of topical solutions available over the counter. Many times they work. If your acne is of the severe nature and doesn't respond to an over the counter topical solution, it may be you need to talk with your doctor about a prescribed treatment. One such prescribed treatment is called Accutane.

Accutane Side Effects
Accutane has been found to be effective in treating more severe types of acne, but can have serious side effects. Before taking this drug, your pharmacist will most likely ask you to read and sign a form stating you understand the possible side effects. You can only begin treatment after verifying you understand and agree to them.

Thinking of starting a family any time soon? One of the most serious possible side effects of taking Accutane is that it can cause possible birth defects in unborn children. It may even cause a woman to miscarry during pregnancy, premature birth, or stillbirth. It is advised that women who are or might be pregnant do not take this medication. Doctors are also requiring women taking the drug to take a pregnancy test every month so they can stop taking it immediately if it yields a positive result.

Physicians also advise against taking Accutane if you plan to become pregnant, and say you should not get pregnant for at least a month after you have stopped taking the drug.

Another harmful side effect of Accutane is the development of mental problems in patients that can even result in suicide. Symptoms of these problems include: feeling sad or anxious, feeling empty, irritability, anger, loss in social activities, sleeping too much or too little, thoughts of suicide, and changes in weight or appetite. These are only a few of the possible side effects associated with the depression this drug is said to cause. If you experience any of these symptoms, or others you feel may be leading to depression, consult your doctor immediately.

Accutane can be a preferred treatment when nothing else has worked to clear up you acne. Severe acne can be very physically painful, and can cause social discomfort as well. Discuss with your doctor whether or not the benefits of taking this medication outweigh the possible side effects, and if it is the right treatment choice for you.

Article Source: http://www.articlebankonline.com

Acne Here, Acne There, Is there a Solution?

By: Hector Milla

Over fifty percent of adults are prone to acne. In fact, almost all people have developed acne at some point. It usually occurs during adolescence because of the hormonal changes; and absolutely in any race, gender, age, of lifestyle.

Unknowingly, acne also has psychological effects on adolescents having acne problems. At this time, social pressure is at its highest, and they don't want to be criticized or laughed at.

Ever heard of the "acne myth"? It says that acne is caused by dirt and oil on the skin's surface which somehow leads to infection under the skin. True, acne happens when sebaceous glands produce oil that is emptied on the skin, together with dead skin cells being shed. When these dead skin cells clump together and clog the pore, it will result to acne. Once the excess skin cells combine with oil, bacteria will develop bringing about inflammatory acne. But contrary to the myth, acne is not caused by dirt.

There are factors that contribute to acne it includes hygiene, hormonal changes, stress, and other factors. With today's technology, acne solutions are widely available, with many brands to choose from; these acne solutions control the production and binding dihydro testosterone or DHT in the skin. By making use of acne solutions, the development of acne can be controlled.

Below is a list of acne solutions and medications that can answer your acne problem:

1. Benzoyl Peroxide; you can get this medication over-the-counter, it causes the skin to dry and peel, and helps in unclogging the pores thereby killing the bacteria
2. Hydrogen Peroxide; too harsh to use, but it can keep the skin clean
3. Azelaic acid; it is an antibacterial cream that unclogs pores
4. Retinoids; a vitamin A derivative and is a proven effective medication for acne control
5. Isotretinoin or accutane; treats severe acne, both nodular and cystic cases
6. Salicylic Acid; unclogs pores and renew the skin
7. Antibiotics; eliminates bad bacteria and fights infection
8. Anti-Androgens; reduces oil and hormone production

Having acne should be able to encourage you in making changes in your lifestyle, especially your eating habits. Avoid anything that will otherwise make the situation worse. For some people, the quickest way to stop acne is not by actually using acne solutions, but by stopping bad habits that makes acne outbreaks frequent. There are times when you become mindful of little details that can help in improving the situation.

However, if you still want to use any acne solution, it is best if you can consult a dermatologist first. People have different skin types, and your medication will usually depend on it and the extent of your problem with acne. Though time is one factor that many people consider when treating their acne, grabbing a strong medicine does not make any sense.

People suffering from acne problems should stay informed of the many options available for treatment. Get yourself educated and make sure that you choose the right approach to acne treatment. The degree of success in treating acne is not the same all throughout.

If after several treatments of acne solutions, there seems to be no improvement, it might be time for you to get medical assistance. Acne is not just a skin condition; it may also be a symptom of hormonal imbalance or other more complicated cases.

Article Source: http://www.articlebankonline.com

Wednesday, March 7, 2007

Doctors' Answers to "Frequently Asked Questions" - Accutane

These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician.

[posted 08/11/1999]
Question: I am a female in my late twenties who has been on accutane for two courses. While the results have been mostly successful, I have been noticing a reutrn of acne on my lower face and neck. There are two options I am considering: 1. going on accutane for a third course or 2. taking one accutane pill a week indefeinitely-- I hear this is an increasingly common treatment some doctors are giving. In either case, I believe I will have a problem finding a doctor to prescribe me accutane, as I had difficulty the last time, since most doctors are too concerned about their own liability to prescribe the medicine to a woman in her child bearing years (even though I am on birth control). So my questions are, what do you know of the effectiveness of the one pill a week treatment, and also, how to find a proaccutane doctor (in the MAnhattan area) without going to dozens of appointments first (my former doctor was ina nother city). Thanks!

Answer: Well, it does work. As to the doctor, I'd call around and see what their office policy is. Some would require, monthly pregnancy tests-but you should be able to find one. There are on-line prescription services that might help.

Accutatne [posted 1/11/99]
Question: I have extremely oily skin (face, scalp, chest, back) and moderately bad acne. 12 months ago I started a 5 month course of accutane (80 mg/day) with extremely pleasing results (drier skin, no acne). But the last two months, my oil production has returned to levels I had before the Accutane, and about 4 weeks ago, I began breaking out again. I have very good hygiene, and am using salicylic acid products. But I can see my old skin returning. I want to do another course of Accutane now. Is this safe? Is it recommended? Before I ever took accutane, I tired almost everything (Benzoyl Peroxide, a range of topical and oral antibiotics, sulfur preparations) and I never achieved clear skin with them. Accutane is the only thing that has worked, but I am frustrated that the effect was so short-lived.

Answer: Usually, we cycle accutane. 3-5 months on and restart when this problem reoccurs. This is the usual course and restarting the Accutane will be necessary.

Accutatne [posted 1/8/99]
Question: I am a 25 year old female and have been on accutane for 3 months. I got results almost immediately and currently my face is clear except for some scarring. I was wondering if I should go off of it now or stay on it for the 4 months as my dermatologist recommended.

Answer: Well, we usually cycle it to reduce other potential toxicities. The cycle length is usually dependent on results, however, 3 or 4 probably doesn't matter much.

Accutane [posted 1/5/99]
Question: I just received a prescription for accutane 20 mg bid from my family practice doctors with no recommendation for special soap, lotion, or antibiotics to accompany my treatment. The doctor plans to treat me for 3 months then "see how it goes." My cousin just started the treatment as well for the first time and is taking 40 mg bid and has been prescribed oral antibiotics for the first month to enhance healing of existing acne. What is the recommended effective dose and length of time one should be treated for? Is a higher dose more effective in the long run and minimize need for future treatments?

Answer: This medication is usually started in small doses and advanced until the acne responds. Then it is cycled as necessary with the aim to diminish long term therapy. Risk in men is pretty small and focuses on liver toxicity in the main. Women can have severe fetal abnormalities along with its other risks.

Accutane and facial laser surgery [posted 1/4/99]
Question: I went on accutane on 3 separate 5 month cycles. My last cycle was completed three months ago. I have excellent results. No scarring at all. Why do I have to wait one year before I can have laser resurfacing done to my face? My plastic surgeon told me that there is a one year waiting period before any resurfacing can be done, but he didn't tell me why. I can't find any supporting facts to explain this. If I only have to wait one month before getting pregnant, why must I wait one year for laser surgery? ".

Answer: I'm not sure. You'll need to ask him.

Accutane & Dry Skin [posted 12/02/98]
Question: My question is about Accutane and the effects of it with the use of a "body building supplement". Will the use of Accutane counter the effects of DHEA and Androstiene? I have been taking accutane for about two months now. I have a bad case of acne problem (as told by my doctors). I want to take DHEA and androstiene because I heard it was really good for boosting up the testosterone Levels and to help build muscles. I have taken it before and it does do what it says. The side effects I have encountered from taking it is a severe acne problem. I break out with acne really bad. So the question is " does Accutane lessen the effects of DHEA and androstiene" and If so "how can I prevent it".

Answer: Accutane will help acne vulgaris no matter what the trigger. However, the superficial lesions you see are probably only the tip of the potential iceberg in terms of side effects.

Accutane & Dry Skin [posted 12/02/98]
Question: In 1983, at the suggestion of my dermatologist, I began taking Accutane. My doctor said it was a new drug which showed promising signs of curing acne. Indeed, the drug worked miracles. My cystic acne has been reduced by 99% ever since. I am now 36 yrs old, and the skin on my face is getting increasingly dry. Particularly around my eyebrows, cheeks, and ears. My skin is constantly flaking. Moisturizers can't keep up. Hydrocortisone cream helps a little. Washing my face with soap greatly exacerbates the problem. Do you know if this is a problem experienced by "early " accutane users? Also, what can I do to help the problem? I almost wish the oil was back in my skin!

Answer: Accutane is only supposed to work when you take it. However, oil production does decrease markedly as one ages (the reason that teens have most of the acne). Have you changed birth control pills or any medications? Also, this may be something different like seborrhea which would respond to a dandruff shampoo(apply full strength and let it sit for a couple of minutes).

Accutane and Alcohol [posted 12/01/98]
Question: Hi, I have been taking accutane for about four weeks, and my question is, would that be ok if I drink alcohol once a week, I mean a drink or two, and what are the side effects if so.

Answer: Occasionally is ok.

Accutane and Cholesterol Levels [posted 11/10/98]
Question: I'm in my second month of accutane for the second time. I know it works, and the side effects are tolerable. But I'm really worried about cholesterol levels, how much is too much? My cholesterol increased from 207 to 249 in the first month, how high can I go? When should I stop? I'm also VERY tired, I just want to sleep ALL day if possible, is this normal for a 25 year old on accutane?

Answer: Usually accutane is pulsed for a couple of months on and a couple of months off. This is usually tolerable to cholesterol levels for a short time (2 years or so).

Is There a Limit To The Number of Accutane Treatments a Person Should Undergo [posted 11/4/98]
Question: I am a 37 year old female who has been treated with accutane for cystic acne three times. The acne clears up as long as I am on the medication and remains clear for about one year after therapy. My new dermatologist suggests a fourth treatment. I am a little concerned about taking it for the fourth time since I had heard that two treatments are the lifetime limit. Is there any truth to this?

Answer: No limit, but insure you have birth control-that is the major risk. Liver functions need to be followed;but, there is no limit to the number of times to take the drug.

Concerns About Sporanox for Fungal Infection While On Accutane [posted 11/4/98]
Question: I am currently taking Sporanox for a fungal infection on my toenails. I also have cystic acne and my dermatologist is putting me on Accutane. Are there any interactions between the drugs? I would like to know if perhaps I should wait to finish the Sporanox and then start the Accutane.

Answer: Well, nothing obvious;but, they both can affect the liver and I really would be reluctant to combine these drugs. The fungal infection will be there after the acne is treated. Also, Accutane tends to be used episodically, cycle it with the Sporonax rather than take them together.

Isotretinoin/Accutane Potential Liver Damage Concerns [posted 10/29/98]
Question: I have heard that the drug - Isotretinoin is very toxic, and it can damage the liver. And the drug - Xepasone is a steroid, and is is harmful to the body for prolong intake, are the above true? I am not able to find any information on these 2 drugs, can you help me out? Thank you.

Answer: Isotretinoin can be toxic if not monitored. In usual doses with regular liver function tests, there is usually no damage to the liver. I'm not familiar with Xepasone, do you have a generic or other name?

Accutane & Height [posted 10/28/98]
Question: Are there any studies to indicate a connection between the drug, Accutane, and height? I have two teenage sons who both took accutane, stopped growing around the same time, and I have since heard there may be a connection.

Answer: Not to my knowledge.

Accutane for Inflammation of the Hair Follicle and Scalp Problems [posted 10/28/98]
Question: I have had foliculitis of the scalp for 25 yrs I took a 2 mo. Treatment of accutane 15 yrs Ago and the condition went away for about 10 yrs. I took it again about 5 yrs ago for 10 days and have not had the problem until about a year ago. I took tetracycline for a year until its effectiveness wore off. I recently took accutane again but for only 6 days. Its amazing how effective it is for me. After only 2 days of treatment. My condition cleared up almost completely. My dermatologist has instructed me to take the accutane until my condition clears up and then retake it when it reappears again. Only taking enough to clear the scalp. Will my body develop a resistance to the accutane if I take it in small intermittent doses? My lips start to peal and my eyes get extremely dry when taking accutane but returns to normal after the treatment. If I keep taking the accutane, is there a chance that the dry lips and eyes will be a permanent condition? I wonder if other people with my condition know that accutane is a very effective treatment. It was very embarrassing to have zits on my scalp. Accutane was an answer to my prayers.

Answer: There will be no resistance to the accutane, the dryness will go away after about 10 days to 2 weeks after stopping the accutane(corneal ulcers are another matter-but less commonly seen).

How Soon Before Surgery Should You Stop Taking Accutane [posted 10/28/98]
Question: I'm 18 years old, female and am currently on Accutane. In just 3 weeks I've seen a remarkable improvement in my skin. I have yet 2 months to go and am very confident my face will totally clear up. Anyway, I'm planning to get a nose job done in about 3 months from now and was wondering if it's safe to have a surgery like this performed after a month off accutane. If not, how long should I wait? I'm just asking because someone told me that accutane makes your skin very sensitive and it won't recover from bruises. Thank you so much for your help.

Answer: Well, I'd wait a couple of months anyway. One is probably ok;but, scarring from plastic surgery is unforgiving.

Surgical Concerns While On Accutane [posted 10/21/98]
Question: I am taking accutane right now. And I am also about to have mandibular jaw surgery. Keep in mind, all incisions during the surgery are made in the inside of my mouth. My dermatologist says to wait until after I am off accutane before I have the surgery in case it effects the healing process. While the oral surgeon says that accutane won't effect the healing at all. It is a big deal whether or not I can take accutane while having the surgery, because if I can't then I have to postpone the surgery for 6 months later. So, can I have jaw surgery and take accutane at the same time?

Answer: Probably not a big issue;but, theoretically could be, go with your surgeons opinion.

How Long Does Accutane Cause Dry, Chapped Lips? [posted 10/20/98]
Question: I have been taking Accutane for a month, and my lips are chapped, the corners of my mouth are cracked and painful. Is there anything I can use to minimize this, and will is continue for the duration of my treatment?

Answer: It tends to last for as long as you use accutane. Sun block(available in lip gloss) helps as does constant use of vasoline jelly or something to restore the oils to your lips.

Accutane Induced Hair Loss? [posted 10/13/98]
Question: I have been off accutane for about 3 yrs., but am wondering if I'm still suffering from it's side effects. I have been experiencing major hair loss. I can actually pull 2 or 3 strands out as I run my fingers through my hair. My mother's dad had very slight hair loss, and my father's dad was pretty much bald. Neither really lost their hair until their late fifties. I guess my question is, is this an effect of the drug, and is their any way to cure or stop the hair loss, even though my hair seems to grow back.

Answer: Not the accutane, there are several medical conditions which can cause the problem, the easiest to diagnose and fix is hyper/hypothyroidism.

Affordable Accutane [posted 10/1/98]
Question: I really like your web site. I am trying to get information on an affordable way to get on accutane therapy if my healthcare provider does not cover it. Any suggestions?

Answer: I have some patients who travel to Mexico for lower prices on drugs. US prescriptions are filled for long periods of time in Mexico at about 1/2 price or lower.

Accutane and Potential for Liver Problems [posted 9/29/98]
Question: I have heard that Accutane has been implicated in liver toxicity. At 10mg/day, how great is the potential for liver damage? What is it about the structure of the drug that causes damage to the liver?

Answer: Accutane is very close in structure to vitamin A-in high doses a known liver toxin-presumably since it is stored in the liver. You should have ongoing liver function tests performed on this drug( at first every 3-4 months and then 6-12);but, in general, few problems would be expected at 10 mg. Also, many physicians would use the drug 3-4 months and then have a 6-8 week "holiday" to avoid any risk of hepatotoxicity.

Accutane and Alcohol [posted 8/13/98]
Question: I have been on accutane for almost 2 months, and so far everything has been great. I was wondering if drinking alcohol affect will affect me? I am afraid to drink because, I am afraid that is may hurt me. Could you respond back to me and tell me if it is ok to drink alcohol while on accutane?

Answer: There is no contraindication or warning associated with the ingestion of alcohol and Accutane.

Accutane [posted 8/11/98]
Question: I have been on 40 mg twice daily for 4 weeks. I was told to wash with any kind of soap and to use Sol Bar 50 sunscreen morning and night as a moisturizer. I have been having breakouts that are worse than when I was not taking accutane. Do you know if it could be the sunscreen or possible improper soap? Prior to this accutane treatment I was taking minocycline twice daily for 2 years in addition to using Retin-A. I stopped taking minocycline 2 weeks ago.

Answer: Did the problem start when you stopped the Minocycline? Sounds like it. Often in severe cases you need two modalities, that is Accutane plus a systemic antibiotic. I would restart the minocycline - check with your doctor.

Accutane and Colitis [posted 8/10/98]
Question: I had my colon removed due to a long battle with colitis. Six months after my surgery, I started Accutane for my cystic acne. Are there any side effects of Accutane that may occur due to my internal pouch. For example, stomach ulcers and pouchitis?

Answer: Accutane can cause cracks around the lips called cheliosis. However, I have not heard of mucosal ulcers or trouble with ostomies, etc. You'll need to try and see, but I suspect you'll see no problems.

Accutane Effects [posted 8/7/98]
Question: I have taken the drug Accutane on three different occasions for the treatment of acne. While the results are not perfect my acne has subsided some. I read that Accutane interferes with vitamin A metabolism. I also read that there is a risk that interruption of vitamin A metabolism might alter normal skin growth, maintenance and repair. Is it possible my metabolism has been so screwed up by the drug that my skin cannot function normally and is subject to consistent breakouts due to the possible malfunctioning of vitamin A metabolism? If so is it possible to reverse this and how would I go about doing it? What kind of doctor would know how to diagnose something such as this?

Answer: This would not be a problem with Accutane, since vitamin A metabolism is not permanently affected. The effects are theoretically possible while taking the drug. However, in clinical practice, I have not seen these types of effects.

Accutane [posted 8/5/98]
Question: I am a twenty-one year old female who completed a five month course of Accutane (for acne) about six months ago. Over the past two months my acne has been slowly coming back. My dermatologist has given me topical treatments to help with the problem, but they have limited effects. I am wondering how my dermatologist will decide if I am going to require a second course of Accutane? If I do require another treatment, what are the chances that my condition will return again?

Answer: You restart the Accutane based on the scarring potential of the acne. Most patients require ongoing treatment since their basic biochemistry doesn't change with the Accutane. Treatment is commonly over 3-4 years at intervals as the acne waxes/wanes.

Accutane Side Effects [posted 8/4/98]
Question: A lot of information is available on the dangers of women becoming pregnant while using accutane. What are the dangers of men using accutane and getting a women pregnant? What are the risks to the mother and especially the child?

Answer: Seems to be much less, but there is concern about this as well. Currently, not a contraindication to the drug. The effect seems to be on the fetus itself and not on the sperm and egg. More research is needed.

Accutane for Skin Cancer [posted 7/27/98]
Question: Can you give my any reference for use of Accutane for skin cancers? - Success and duration of treatment.

Answer: I have never used it for this. I would check with the scientific department of Roche: 800-526-6367.

Accutane [posted 7/24/98]
Question: How effective is accutane and what are the risks and side effects?

Answer: Accutane is an extremely effective in the treatment of Acne Vulgaris. Many patients have near complete resolution of their acne. It will take a while to work (6-8 weeks) and there are some potential risks. Cholesterol may be elevated and there have been a few cases of association with inflammatory bowel disease, liver toxicity has occurred, and the most potentially serious is pseudotumor cerebri (an elevated pressure in the brain). It is absolutely contraindicated in pregnancy and is known to cause severe birth defects. However, most patients have few/no problems taking the drug.

Accutane [posted 7/24/98]
Question: I have been taking Accutane for three weeks, and I am developing severe breakouts. Can I use Retin-A to calm them down?

Answer: I wouldn't until you give the Accutane some more time. It usually takes 6 weeks for results.

Accutane an Sun [posted 7/16/98]
Question: I was wondering if Accutane is bad to take if I am going to be in the sun over spring break?

Answer: There are some cases of sun sensitivity. The face and sun exposed areas tends to be easily sunburned. I would be very careful of sun exposure while taking this medication unless you have a gradual exposure without problems.

Accutane
Question: I have been taking Accutane for approximately 1.5 months. I also had laser surgery on my eyes to correct nearsightedness. The procedure was a large success but I am experiencing corneal hazing. Corneal hazing is caused by the build up of collagen on the cornea. It seems to be a lot of hazing. Does Accutane increase the production of collagen or protein? If Accutane increases protein/collagen production might I have a problem losing the corneal hazing?

Answer: There is no obvious relationship between Accutane and corneal problems.

Accutane
Question: How close is Vitamin A to Accutane? Would taking a daily dosage of Vitamin A help at all?

Answer: They are structurally similar, although accutane is a different chemical. Topical Vit A might work-- system doses probably won't. Big doses of Vitamin A can be lethal, which is why you can't buy it by itself.

Accutane & Blood Levels
Question:Today I started a course of accutane because I have had acne for 8 years and nothing has worked on my face yet. I hope Accutane is going to work for me. I have taken all of the topical and oral medications that are on the market to kill oil and bacteria, so far nothing has worked. I am worried about my blood levels, they are elevated and I hear that Accutane will raise them even more. Cholesterol 261 Trigleserates 361. It is genetic in my family to have these high levels, both mom and dad are on cholesterol lowering medicines, Questerine and Mevacore. I'm 23 years old and still fighting this skill disease, in your opinion do you feel that I will be fine in the rest of the treatment? I am going to be monitored closely by my internist and my dermatologist. I will take a book test once every 2 weeks. They feel that I will be fine if closely monitored. I'm a college student who lives 100 miles from home and it is hard to see my doctor on a regular basis, once a month is what I have been doing.

Answer:I think their monitoring program will be fine-they will be able to pick up elevating cholesterol before it is a problem. You should be able to get the tests done locally and mailed to your doctor. Most physicians could do this on the phone-pay him if necessary.

Accutane Results
Question:Could you please share the results of patients using Accutane?

Answer: Accutane works pretty well at the price of reddened skin. I'd use it if you have severe acne vulgaris.

Side Effects
Question:How serious are the side effects of the acne medicine Accutane?

Answer: Accutane(isotretinoin is a variation of Vitamin A. Consequently, the toxicity is similar to Vitamin A toxicity-chelitis(mouth sores),-90%, conjunctivitis, bone hyperostosis, arthralgias. Rare but severe reactions include pseudotumor cerebri(increased pressure in the brain)-it should absolutely not be used in women who could become pregnant. However, in general the side effects are pretty minimal.

30 Year Battle
Question: I am 49 and have had excess oil, enlarged pores and get pus daily on my nose. I have fought with this since I was 19 and wonder if accutas inould be too severe of a medication to help me. I have taken sumycin and tetracycline, but now get nauseated whenever I try to take these two drugs. Would accutane be a drug that I should consider to cure my problem for good?

Answer: Sounds like a good option, generally well tolerated without side effects-avoid pregnancy.

Night Blindness
Question: I know that Accutane causes night blindness in 1% of its users. I have been wondering why it does so.

Answer: It is similar in structure to Vitamin A-a vitamin needed for night vision. It seems to have some effect in some patients in blocking effective night vision.

Accutane & Pregnancy
Question: I am a 25 year old female. My doctor would like for me to start accutane. I have tried Differn, Rentin-A, Benzamycin, SalAc Wash, Brevoxyl, Azelex, and Murad. Nothing has seemed to work. Currently, I have been using differn and my face has broken out the worst in my entire life. I would have no problem trying accutane except for the fact of the birth defects. I am not sexual active now. However, I do plan on having children within the next five years. What is the current research on the long term effects of accutane for child births? Can you refer me to look anywhere for help?

Answer: The fetal toxicity of accutane seems to be limited to the time the drug is taken. While there is a washout period, it does not persist as a risk factor. I would ask the company if you have further questions-Roche 800-526-6367.
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What is Accutane?

Accutane, also known as isotretinoin, is a powerful oral medication used to treat the most severe form of acne (nodulo-cystic acne). This severe type of acne is characterized by the appearance of nodules and cysts about the size of pencil erasers or larger. They can be painful and unsightly, and left untreated, can result in permanent scarring. Accutane works by helping the sebaceous gland to "mature." Because side effects are serious, patients must be carefully monitored by a doctor.

History of Accutane

Prior to the development of isotretinoin, the mainstay treatment of severe acne was oral antibiotics such as the tetracyclines and erythromycin. While these drugs have proven efficacy, they worked against only one contributing factor of acne – the Propionibacterium acnes bacteria. The antibiotics gradually became less effective over time as more resistant strains of the bacterium became prominent.

An early, effective treatment of acne was high doses of the fat-soluble vitamin A. At these dose levels (sometimes 500,000 IU per day) effects such as reduced production of sebum and dry hair could be noticed. However the vitamin also had many other prominent side effects which inhibited its widespread use.

The development of the retinoic acid derivative isotretinoin (13-cis-retinoic acid), and its release in 1982 by Hoffmann-La Roche, was a great step forward in the treatment of acne. The synthetic compound provided better therapeutic benefit than vitamin A, while also producing fewer adverse effects. In February 2002, Roche's patents for isotretinoin expired and there are now many other companies selling cheaper generic versions of the drug.

Today isotretinoin is usually prescribed after other acne treatments have failed to produce results. The treatment of acne usually begins with tropical medications (e.g. benzoyl peroxide, adapalene, etc), followed by oral antibiotics (or a combination) and finally isotretinoin therapy. This is because other treatments, while less effective than isotretinoin, are associated with far fewer adverse effects and lower cost.