Hormones And Skin

By Ramzaj

Man's sexual hormones and skin. Testosterone, other androgens also that on them influences.

Formation of dermal grease is boosted by man's sexual hormones - androgens. The most active androgens - testosterone, 5-testosterone (dihydrotestosterone, DHT) and 5-androstendiol. Despite of the name, man's sexual hormones is and at women. Androgens are produced by sexual glands: at men in testicles, at women - in ovaries. Both female, and man's sexual glands are checked by hormones of a pituitary body - a member which is being a brain.








testosterone








dihydrotestosterone (DHT)








5-androstendiol

In a skin activity of androgens strengthens some ferments (an androgen - reductases I of type, 5-alpha-reductase). These ferments transmute less active androgens into more active: testosterone and DHT (5-testosterone). Crates of a follicle have receptors of androgens and can accept signals from them.

Changes in a level of the hormones, descending during puberty, explain occurrence of spots in teenagers.

Activity of sebaceous glands can variate and at some diseases of endocrine system: a pituitary body, paranephroses, or man's and female sexual glands. The quantity of dermal grease on a skin thus increases or contracts.

The reinforced formation of dermal grease, seborrhea and acnes can educe not only from pinch of the common level of sexual hormones in a blood. The most part of testosterone in a blood is bound by special protein SHBG (the globulin binding sexual hormones). Deficiency SHBG result ins to strengthening of the free testosterone which is joined to receptors in sebaceous glands. Activity of ferment 5-alpha-reductases can be increased at some people. As a result at these people on sebaceous glands react more active androgens. Sensitivity of a skin and sebaceous glands to androgens at some people also appears higher.

Female sexual hormones - the estrogens used in hormonal contraception, reduce formation of dermal grease. The same effect drugs - can yield antiandrogens.

Purpose of drugs of testosterone to boys up to period of puberty (or progesterones with androgenic properties) boosts formation of dermal grease ice and promotes development of acnes.

And still, androgens - not the single hormones influencing operation of sebaceous glands. Similar influence is rendered with a growth hormone and an insulinoid growth factor.

Some states related to the hormonal status of the person, can worsen a state of a skin. It is a syndrome of polycystic ovaries (at women), Cushing syndrome (from the long-term treatment by steroid hormones). Also failure of ferments which control formation of sexual hormones: for example, sterol-hydroxylases, that descends very seldom, and also depression and the strong psychologic stress.

© Ramzaj
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